Peptide Database

Peptide NameC3a

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC383H636N126O114S11

DescriptionStandard

        SVQLMERRMDKAGQYTDKGLRKCCEDGMRDIPMPYSCQRRARLITQGESCLKAFMDCCNYITKLREQHRRDHVLGLAR
    

Molecular Weight9182.64 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.58

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0716

GRAVY Index-0.79

Hydrophobic Moment 0.68

Boman Index-0.31

Instability Index48.01

Aliphatic Index 62.56

Aromaticity 0.0513

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3968.41

LogP -42.72

H-bond Donors 148.0

H-bond Acceptors 133.0

Rotatable Bonds 319.0

Heavy Atoms 634.0

Ring Count 8.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392066 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsThere are 3 disulfide bonds formed between cysteine residues at positions 23 and 50, 24 and 57, 37 and 58.

Bio-Activity Profile

Function

Chemotactic Immunomodulatory Signaling peptide

TargetC3a receptor (Rat); C5a1 receptor (Rat)