Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC165H250N46O49S6

DescriptionStandard

        DHYQCVKNGGFCLYSACPTYSRIVGTCYNGKAKCC
    

Molecular Weight3854.42 Da

Isoelectric Point (pI)8.63

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0795

GRAVY Index-0.19

Hydrophobic Moment 0.46

Boman Index0.02

Instability Index31.43

Aliphatic Index 44.57

Aromaticity 0.1429

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1540.98

LogP -18.17

H-bond Donors 60.0

H-bond Acceptors 59.0

Rotatable Bonds 121.0

Heavy Atoms 266.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066256 VERIFIED: YES

Provenance & Taxonomy

OrganismOctodon degus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)