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MYP_098424
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C29H44N8O10
Standard
Sequence
YLAGNQ
Physicochemical Analysis
664.71 Da
5.52
-0.24
-0.45
-0.0401
-0.52
0.11
0.13
-18.38
81.67
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
315.23
-3.39
10.0
10.0
20.0
47.0
1.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0154225 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
15 mmHg
SBP decrease
PaperRational design of angiotensin-I-converting enzyme inhibitory peptides by integrating in silico modeling and an in vitro assay. PMID23740817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23740817/
RECORD: Rec_0172683 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
14 μM
IC50
PaperRational design of angiotensin-I-converting enzyme inhibitory peptides by integrating in silico modeling and an in vitro assay. PMID23740817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23740817/
RECORD: Rec_0181560 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
14.0
IC50
PaperWang W., Gonzalez de Mejia E.. A new frontier in soy bioactive peptides that may prevent age-related chronic diseases. Comp. Rev. Food Sci. Food Safety, 2005, 4, 63 -77.
RECORD: Rec_0184925 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 66.7%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0202680 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
ACE inhibitory peptide
3847
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
PaperIsolation and characterization of peptides with antihypertensive activity in foodstuffs | Vegetable foods: a cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities PMID24915368;23598130 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
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