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MYP_098423
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C15H30N4O4
Standard
Sequence
IAK
Physicochemical Analysis
330.42 Da
8.75
0.76
0.55
0.2530
0.80
0.97
0.17
6.67
163.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
147.54
-0.44
5.0
5.0
11.0
23.0
0.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0135723 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSedaghati M., Ezzatpanah H., Boojar M. M., Ebrahimi M. T., Aminafshar M.. Plasmin digest of kappa-casein as a source of antibacterial peptides. J. Dairy Res., 81, 245-51, 2014.
RECORD: Rec_0149086 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperMiguel M., G¨®mez-Ruiz J. A., Recio I., Aleixandre A.. Changes in arterial blood pressure after single oral administration of milk-casein-derived peptides in spontaneously hypertensive rats. Mol. Nutr. Food Res., 54, 1422-1427, 2010.
RECORD: Rec_0160171 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
15700 μM
IC50
PaperChanges in arterial blood pressure after single oral administration of milk-casein-derived peptides in spontaneously hypertensive rats PMID20397194 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20397194/
RECORD: Rec_0225064 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal] [Animal]; Ovis aries [Animal]
Casein-derived peptide
9913;9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Antimicrobial Antibacterial
100 μM
MIC
RECORD: Rec_0225167 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli; Staphylococcus aureus; Lactobacillus casei; Lactobacillus acidophilus
MIC
PaperPlasmin digest of kappa-casein as a source of antibacterial peptides | Sedaghati, M. et al. | DOI: 10.1017/S0022029914000120 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
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