MYP_098376
AA-RP-1
Antimicrobial
Antiparasitic
▸
Anti-Leishmania
▸
Antileishmanial
Antiparasitic
▸
Antiprotozoal
▸
Anti-Trypanosoma
Antiparasitic
▸
General antiparasitic
▸
Antiparasitic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
AXYKKFKKKLLKSLKRLG
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0001224
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
AA-RP
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
Anthryl-alanine-substituted (position 2) congener of the parent peptideRP-1
Bio-Activity Profile
Antimicrobial
Host-defense peptide
Antiparasitic
Antileishmanial
Anti-Trypanosoma cruzi
Leishmania infantum chagasi MHOM/BR/00/1669
12.5 mg/kg
Microscopy (Giemsa staining)
RECORD: Rec_0002546
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
AA-RP
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
Anthryl-alanine-substituted (position 2) congener of the parent peptideRP-1
Bio-Activity Profile
Antimicrobial
Host-defense peptide
Antiparasitic
Antileishmanial
Anti-Trypanosoma cruzi
Leishmania infantum chagasi MHOM/BR/00/1669 (promastigote)
50 μg/mL
Growth inhibition; Microscopy (Giemsa staining)
RECORD: Rec_0110854
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
AA-RP
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
Anthryl-alanine-substituted (position 2) congener of the parent peptideRP-1
Bio-Activity Profile
Antimicrobial
Host-defense peptide
Antiparasitic
Antileishmanial
Leishmania braziliensis (promastigote)
10 μg/mL
MIC
RECORD: Rec_0185932
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
AA-RP
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
Anthryl-alanine-substituted (position 2) congener of the parent peptideRP-1
Bio-Activity Profile
Antimicrobial
Host-defense peptide
Antiparasitic
Antileishmanial
Leishmania major (promastigote)
100 μg/mL
Growth inhibition; MTT assay