Peptide Database

Peptide NamepbpB signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC182H292N46O39S5

DescriptionStandard

        MIQMPKKNKFMNRGAAILSICFALFFFVILGRMA
    

Molecular Weight3908.87 Da

Isoelectric Point (pI)11.11

Net Charge (pH 7.0)4.49

Net Charge (pH 7.4) 4.25

Charge Density (pH 7.0) 0.1320

GRAVY Index0.90

Hydrophobic Moment 0.52

Boman Index0.29

Instability Index39.56

Aliphatic Index 100.59

Aromaticity 0.1471

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1366.19

LogP -5.70

H-bond Donors 48.0

H-bond Acceptors 49.0

Rotatable Bonds 132.0

Heavy Atoms 272.0

Ring Count 6.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047886 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

MethodSecretion phenotype assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/