Peptide Database

Peptide NameCrotalus adamanteus antivenin

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length1652 amino acids

Chemical FormulaC8227H13016N2218O2504S58

DescriptionStandard

        MEGMALYLVAALLIGFPASSFGALYTFITPGVLRTDTEEKILVEAHGDNAPKQLDISVHDFPRKQKILYQTRVDMNPAGGMLVTPTITIPAKDLNKDSRQNQYVVVQVTAPGLRLEKVVLLSYQSGFVFIQTDKGIYTPGSPVRYRVFSMDHNMHRMDKTVIVEFQTPQGIVVSSNPVNPASSLIRPYNLPELVSFGTWKAVAKYENSPEESYTALFDVREYVLPGFEVRVQPSEKFLYIDGNTDFHVSITARYLYGKRVEGVAFVLFGVKIDGNKKSIPESLTRIPIIDGDGEATLERHTLSRRFQRLNDLVGHNLYVSVTVITDSGSDMVVTEQSGIHIVTSPYQISFTKTPKYFKPGMPYELMVYVTNPDGSPAANVPVVSESIHSKGTTLSDGTAKLILNTPLNIQSLSITVKTNHRDLPRERQAMKSMTATAYQTQGGSGNYLHIAITSTEIKPGDNLPVSFNVRGNANSLNQIQYFTYLILTKGKIFKVGRQPRGAGQNLVTMTLPITPDLIPSFRFLAYYQVGNSEIVADSVWVDVKDTCMGTLVVKGASSRDNRIQKPGAAMKIKLEGDPGARVGLVAVDKAVYVLSDEYKISQTKIWDTIEKSDFGCTAGSGQNNLGVFEDAGLALATSTSLNTKQRSDAKCPQPENRRRRRSVVLLDSKASKAAQFPDQALRKCCEDGMHENPMGYSCEKREKYIQEGDACKAAFLECCRYIKGIHDENKREDELFLARSDFEDEFFGEDNIISRSDFPESWLWLTENLNAVPNNEGISSKTVPFYLRDSITTWEVLAVSITPTKGICVAEPYEITVMKDFFIDLRLPYSVVKNEQVEVRAILYNYVDDDIDVRVELLHNPAFCSVATETQRYRTQVTIKALSSWAVPFVIVPLQQGLHDIEVRASVRGQLASDGVKKKLKVVPEGMRKDIVTVIELDPSTKGVGGTQEQLVKANELDGKVPDTEIETKISVQGDRVAQIVENSIDGNKLSHLIITPSGCGEQNMITMTPSVIATYYLDTTGQWETLGVDRRTEAVQQIKKGYAQQLVYKKADHSYAAFVNRDSSSWLTAYVVKVFAMATKVVPDISHEIICGGVKWLILNRQQPDGVFKENAPVIHGEMLGGTKGAEPEVSLTAFILIALLESRSICNEHINILESSINKAADYLLKKYEKLQRPYTTALTAYALAAAGLLNDDRVLMAASTERNRWEEHNAYTYNIEGTSYALLALLKMEKFAEANPVVRWLTDQKYYGGTYGQTQATVVGFQGLAEYEIAMPSHKDLNLDIVIKLPEREVPISYRIDATNALRAQTTETKLNEDFTVSASGDGKATMTILTVYNAQLREDANVCNQFHLEVSVERIDSNLKQAKGAKETLKLKICTRYLGEVDSTMTIIDVSMLTGFLPDAEDLTRLSKGVDRYISKFEIDNNMAQKGAVIIYLDKVSHSEDECLQFRIQKHFEVGFIQPGSVKVYSYYNLDEQCTRFYHPDKGTGLLNKICHGNVCRCAEETCSLLNQQKKIDLQLRIQKACEPNVDYVYKAKLLRIEEKDASDIYVMDVLEVIKGGTDRNPQAKPRQYVSQRKCQEALNLKVNNDYLIWGLSSDLWHKKDEISYLITRNTWIERWPNEDECQDEEFQNLCNDFTQLSNTLTIFGCPN
    

Molecular Weight184920.48 Da

Isoelectric Point (pI)5.87

Net Charge (pH 7.0)-19.09

Net Charge (pH 7.4) -21.63

Charge Density (pH 7.0) -0.0116

GRAVY Index-0.28

Hydrophobic Moment 0.81

Boman Index0.00

Instability Index37.55

Aliphatic Index 89.19

Aromaticity 0.0835

Extinction Coeff. Reduced 189320.00

Extinction Coeff. Oxidized 190945.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0342739 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyMonoclonal antibody

Tax ID9940

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation

Bio-Activity Profile

Function

Immunomodulatory Coagulation factor replacement Enzyme replacement

Half-Life12 to 23 hours [FDA label]