Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC392H595N113O113S13

DescriptionStandard

        MEAFGVACAVNLACMFILENTAVPFSEEVGSIDSPVGEHQQPGGESMRPPEHFRFKRQSHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight9115.45 Da

Isoelectric Point (pI)6.38

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.81

Charge Density (pH 7.0) -0.0150

GRAVY Index-0.09

Hydrophobic Moment 0.49

Boman Index0.05

Instability Index79.60

Aliphatic Index 52.32

Aromaticity 0.0976

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3574.28

LogP -38.28

H-bond Donors 130.0

H-bond Acceptors 129.0

Rotatable Bonds 293.0

Heavy Atoms 631.0

Ring Count 18.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385984 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus tshawytscha [Animal]

FamilyHepcidin

Tax ID74940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal