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MYP_098289
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Basic Information
C7A-D21K
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C145H268N46O31S
Standard
Sequence
KILRGVAKKIMRTFLRRISKKILTGKK
Physicochemical Analysis
3184.03 Da
12.00
10.75
10.54
0.3983
-0.30
0.89
-0.29
42.29
115.56
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1310.35
-9.03
50.0
43.0
120.0
223.0
1.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0261265 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
NK-2-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
E42/02
8.4±0.2 μM
IC50
PMID23893605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893605/
RECORD: Rec_0268749 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0280717 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 24962950 PMID24962950 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24962950/
RECORD: Rec_0299070 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HROC32
>80 %
Cell viability assay
PaperPubMed PMID: 24962950 PMID24962950 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24962950/
RECORD: Rec_0306367 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
NK-2-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
HCT-116
12.5 μM
Cell viability assay
PaperHost defense peptides for treatment of colorectal carcinoma - a comparative in vitro and in vivo analysis PMID24962950 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24962950/
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