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MYP_098274
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Basic Information
TP
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C96H132N28O14
Standard
Sequence
VRRFPWWWPFLRR
Physicochemical Analysis
1902.25 Da
12.00
3.73
3.52
0.2872
-0.79
0.47
-0.23
139.58
52.31
0.3846
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
689.91
0.64
27.0
18.0
52.0
138.0
10.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0272182 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Bacillus subtilis KCTC 3068
8 μg/mL
MIC
PaperAntimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides
RECORD: Rec_0282891 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
190 μg/mL
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/16997878/ PMID16997878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16997878/
RECORD: Rec_0283344 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID8706838;10606506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8706838/
RECORD: Rec_0293036 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
[Refer PubMed ID - 8706838: Aspergillus fumigatus (
250 μg/mL
MIC
PMID8706838;16563706;12681513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8706838/
RECORD: Rec_0302826 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
cathelicidin family
9823; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial cathelicidin family Antibacterial Host defense
PaperPDB 2I1D structural record; NMR; chain A; residues 1-13
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