Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length478 amino acids

Chemical FormulaC2363H3690N614O681S24

DescriptionStandard

        MFQLIIIVVLTIVSCTTGENPAFQVTLNNKGLQYGKHVAAGWIQDRLGLITLPDISGEALLVHYTLSGIKITKCDFPEPSVEFYQNVTGLKSSITGLSIAVNGSWATHLGVIHDGGTFDLAVFNVGVTSVVKLGKDSNGHLSVTNVNCDAKVGDVQMNFYGGQSWIFKPFLKYYKGHVLAAIQANICPNVEDFIVKVESHLQALNVSIIVDSFLSLDLNLTSSPVIDSTSLNLPLKGQFYSIKTHKEPPFVAQPFTMPKQTDYMLSIGLSDFTANSASYAYYSDGQLMMYIDDKMIPPASPVHLNTSSMGPYIPQLPQMFPNLLMKLLVYARNCPMFSFQPGAVKLGLPLAIKAFAIQPNTSLTPLFKLHVMANISGKMWIGDGRLRGSVMMDNFKLTLAGSEVGAFKTTPFGKTIEDWTTDGSPAQHQQDVWQRCCFTQNEKRSAGVLRSNGGAGISSRCFRFCDSDNRRTLQLTKS
    

Molecular Weight52365.84 Da

Isoelectric Point (pI)8.44

Net Charge (pH 7.0)4.38

Net Charge (pH 7.4) 3.39

Charge Density (pH 7.0) 0.0092

GRAVY Index0.06

Hydrophobic Moment 0.61

Boman Index0.15

Instability Index39.80

Aliphatic Index 90.73

Aromaticity 0.0962

Extinction Coeff. Reduced 53860.00

Extinction Coeff. Oxidized 54360.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383579 VERIFIED: NO

Provenance & Taxonomy

OrganismSphaeramia orbicularis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria