Peptide Database

Peptide NameProthyroliberin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length165 amino acids

Chemical FormulaC812H1322N260O265S6

DescriptionStandard

        QALPGEGDPSLDELLQLLRSMLTQMEDENHANGEQTEWLEKRQHPGKREEDGGRLRRQHPGKRLSLEQVMLEEPSEQSELSKRQHPGKRYLMLLHKRQHPGRRELQEASLAKRQHPGKRLCEDWSETGCDPASVLLELLDRSGAEEKRQHPGKRLELEDDLTEQE
    

Molecular Weight19159.16 Da

Isoelectric Point (pI)5.68

Net Charge (pH 7.0)-6.49

Net Charge (pH 7.4) -7.19

Charge Density (pH 7.0) -0.0393

GRAVY Index-1.34

Hydrophobic Moment 0.65

Boman Index-0.35

Instability Index82.08

Aliphatic Index 68.61

Aromaticity 0.0182

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8582.43

LogP -93.63

H-bond Donors 294.0

H-bond Acceptors 272.0

Rotatable Bonds 670.0

Heavy Atoms 1343.0

Ring Count 23.0

Amide Bonds 180.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273127 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyTRH

Tax ID7962

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGln43 Pyroglutamylation; Pro45 Amidation; Gln58 Pyroglutamylation; Pro60 Amidation; Gln84 Pyroglutamylation; Pro86 Amidation; Gln98 Pyroglutamylation; Pro100 Amidation; Gln114 Pyroglutamylation; Pro116 Amidation; Gln149 Pyroglutamylation; Pro151 Amidation

Bio-Activity Profile

Function

Hormone Neuropeptide