Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC748H1171N223O217S6

DescriptionStandard

        MARVQFKPRESTDAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEEGRDEMAVGSHAKGHNHNSIGVCLVGGIDDKGKFEANFTPAQMQSLRSLLVTLLAKYKGAVLRAHHDVAPKACPSFDLKRWWETNELVTSDRG
    

Molecular Weight16952.05 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.19

Net Charge (pH 7.4) 2.49

Charge Density (pH 7.0) 0.0211

GRAVY Index-0.50

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index40.16

Aliphatic Index 74.24

Aromaticity 0.0795

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7091.72

LogP -71.94

H-bond Donors 250.0

H-bond Acceptors 234.0

Rotatable Bonds 566.0

Heavy Atoms 1194.0

Ring Count 29.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0092169 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage HZ2R8 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0420738 VERIFIED: NO