Peptide Database

Peptide NameAtrial natriuretic factor

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC116H197N45O42S4

DescriptionStandard

        NNRGSSGCFGSRIDRIGSMSSMGCGGSRKG
    

Molecular Weight3022.34 Da

Isoelectric Point (pI)10.72

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.51

Charge Density (pH 7.0) 0.1247

GRAVY Index-0.69

Hydrophobic Moment 0.61

Boman Index-0.19

Instability Index45.93

Aliphatic Index 26.00

Aromaticity 0.0333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1445.93

LogP -26.44

H-bond Donors 56.0

H-bond Acceptors 50.0

Rotatable Bonds 106.0

Heavy Atoms 207.0

Ring Count 1.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239899 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]

FamilyAtrial natriuretic factor

Tax ID7904

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-24

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Receptor modulation

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour