Peptide Database

Peptide NameProtegrin 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length179 amino acids

Chemical FormulaC873H1406N246O262S6

DescriptionStandard

        METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGRVKQCVGTVTLKEIRGNFDITCNQVSGPFSFEVLLGVRRVVQPLDQFPAATSGREHPPTLAPPSPEPQVSRTGSVIL
    

Molecular Weight19732.38 Da

Isoelectric Point (pI)6.60

Net Charge (pH 7.0)-0.43

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0024

GRAVY Index-0.27

Hydrophobic Moment 0.84

Boman Index-0.03

Instability Index44.44

Aliphatic Index 88.72

Aromaticity 0.0559

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8097.65

LogP -95.35

H-bond Donors 279.0

H-bond Acceptors 269.0

Rotatable Bonds 633.0

Heavy Atoms 1387.0

Ring Count 32.0

Amide Bonds 193.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033969 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal

RECORD: Rec_0082896 VERIFIED: NO