Peptide Database

Peptide Name[Pro3]GIP

Function Ontology

Hormonal / Endocrine ▸ Hormonal activity

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC226H338N60O64S

DescriptionStandard

        YAPGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
    

Molecular Weight4951.53 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.61

Charge Density (pH 7.0) 0.0222

GRAVY Index-0.75

Hydrophobic Moment 0.36

Boman Index-0.03

Instability Index37.90

Aliphatic Index 69.76

Aromaticity 0.1429

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2038.88

LogP -17.47

H-bond Donors 68.0

H-bond Acceptors 68.0

Rotatable Bonds 164.0

Heavy Atoms 351.0

Ring Count 11.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408640 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Antidiabetic Hormonal activity

TargetGIP receptor (Mouse)