Peptide Database

Peptide NameAlpha-mammal toxin BmK-M8

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC293H435N83O99S8

DescriptionStandard

        GRDAYIADSENCTYFCGSNPYCNDVCTENGAKSGYCQWAGRYGNACYCIDLPASERIKEPGKCG
    

Molecular Weight6960.60 Da

Isoelectric Point (pI)4.77

Net Charge (pH 7.0)-2.31

Net Charge (pH 7.4) -2.65

Charge Density (pH 7.0) -0.0361

GRAVY Index-0.63

Hydrophobic Moment 0.49

Boman Index-0.06

Instability Index30.72

Aliphatic Index 38.28

Aromaticity 0.1250

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2949.50

LogP -37.53

H-bond Donors 109.0

H-bond Acceptors 105.0

Rotatable Bonds 220.0

Heavy Atoms 483.0

Ring Count 12.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339310 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilySodium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-63; 16-36; 22-46; 26-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense

RECORD: Rec_0366487 VERIFIED: NO