Peptide Database

Peptide NameBeta-defensin 401

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC306H509N99O72S7

DescriptionStandard

        MRLHHLLLALLFLVLSAGSGFTQGVRTFVTCRINRGFCVPIRCPGHRRQIGTCLGPRIKCCR
    

Molecular Weight6951.39 Da

Isoelectric Point (pI)11.47

Net Charge (pH 7.0)9.70

Net Charge (pH 7.4) 9.24

Charge Density (pH 7.0) 0.1565

GRAVY Index0.39

Hydrophobic Moment 0.76

Boman Index0.05

Instability Index23.15

Aliphatic Index 103.71

Aromaticity 0.0645

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2731.86

LogP -25.21

H-bond Donors 106.0

H-bond Acceptors 92.0

Rotatable Bonds 227.0

Heavy Atoms 484.0

Ring Count 10.0

Amide Bonds 64.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0014222 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function