Peptide Database

Peptide NameAntimicrobial peptide, Hepcidin-22

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC99H159N29O25S9

DescriptionStandard

        FPICIFCCGCCHRSKCGMCCKT
    

Molecular Weight2444.09 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.77

Net Charge (pH 7.4) 2.39

Charge Density (pH 7.0) 0.1257

GRAVY Index0.78

Hydrophobic Moment 0.15

Boman Index0.14

Instability Index53.09

Aliphatic Index 35.45

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 848.71

LogP -9.02

H-bond Donors 38.0

H-bond Acceptors 38.0

Rotatable Bonds 77.0

Heavy Atoms 162.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288548 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyHepcidin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-10; 7-20; 8-19; 11-16

Bio-Activity Profile

Function

Antimicrobial