Peptide Database

Peptide NameSLAY-screened peptide P1104

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC100H167N31O26

DescriptionStandard

        PLGTPPRFHLRISTLIRSTG
    

Molecular Weight2219.59 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.05

Net Charge (pH 7.4) 2.94

Charge Density (pH 7.0) 0.1523

GRAVY Index-0.14

Hydrophobic Moment 0.66

Boman Index-0.00

Instability Index38.47

Aliphatic Index 97.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 900.18

LogP -9.33

H-bond Donors 34.0

H-bond Acceptors 30.0

Rotatable Bonds 68.0

Heavy Atoms 157.0

Ring Count 5.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096157 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/