Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC245H417N71O82S8

DescriptionStandard

        MSTKDFNLDLVSVSKKDSGASPRITSISLCTPGCKTGALMGCNMKTATCNCSVHVSK
    

Molecular Weight5925.88 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0620

GRAVY Index-0.02

Hydrophobic Moment 0.31

Boman Index0.02

Instability Index26.72

Aliphatic Index 66.67

Aromaticity 0.0175

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2466.66

LogP -35.53

H-bond Donors 92.0

H-bond Acceptors 95.0

Rotatable Bonds 200.0

Heavy Atoms 406.0

Ring Count 4.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401684 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0425911 VERIFIED: NO