Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC456H715N125O133S12

DescriptionStandard

        YPNNDFGCEECKLKENNIFSKPGAPVYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKEVKRVIVNDVKLVNHTDCHCSTCYYHKF
    

Molecular Weight10461.09 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)4.92

Net Charge (pH 7.4) 4.39

Charge Density (pH 7.0) 0.0535

GRAVY Index-0.37

Hydrophobic Moment 0.69

Boman Index-0.06

Instability Index53.51

Aliphatic Index 59.24

Aromaticity 0.0978

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4157.42

LogP -43.02

H-bond Donors 151.0

H-bond Acceptors 153.0

Rotatable Bonds 340.0

Heavy Atoms 726.0

Ring Count 18.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0130176 VERIFIED: NO

Provenance & Taxonomy

OrganismClarias gariepinus [Animal]

FamilyGlycoprotein hormones

Tax ID13013

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide8-32; 11-61; 29-82; 33-84; 60-87

Other Mods53:N-linked (GlcNAc...) asparagine; 78:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min