Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC537H879N133O154S4

DescriptionStandard

        MKNSNLFKIASVTSVVSLFAIATFLMGSSEGIAGLASIDFSSGHQFALDLSTNLGISRKTAYVAIGVIMTTGDVLTILSLLAVVLGGTGLITAAMVATAKKLAKKYGKKYAAEW
    

Molecular Weight11790.78 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)4.58

Net Charge (pH 7.4) 4.29

Charge Density (pH 7.0) 0.0402

GRAVY Index0.72

Hydrophobic Moment 0.64

Boman Index0.31

Instability Index9.62

Aliphatic Index 115.61

Aromaticity 0.0789

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4556.78

LogP -42.65

H-bond Donors 163.0

H-bond Acceptors 164.0

Rotatable Bonds 397.0

Heavy Atoms 828.0

Ring Count 11.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148346 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus swezeyi [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal