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MYP_098045
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Basic Information
C7A
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C143H261N45O33S
Standard
Sequence
KILRGVAKKIMRTFLRRISKDILTGKK
Physicochemical Analysis
3170.95 Da
12.00
8.76
8.54
0.3243
-0.29
0.89
-0.26
45.43
115.56
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1321.63
-9.68
50.0
43.0
118.0
222.0
1.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0392721 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID23893605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893605/
RECORD: Rec_0400813 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
NK-2-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
HROC60
25 μM
Cell viability assay
PaperHost defense peptides for treatment of colorectal carcinoma - a comparative in vitro and in vivo analysis PMID24962950 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24962950/
RECORD: Rec_0405628 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
E42/02
37±4.3 μM
IC50
PMID23893605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893605/
RECORD: Rec_0410875 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
32 μg/mL
MBC
PMID21474443 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21474443/
RECORD: Rec_0416082 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HROC18
>55 %
Cell viability assay
PaperPubMed PMID: 24962950 PMID24962950 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24962950/
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