Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC334H518N102O101S2

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIRMMGTGGVVSLPDEANAQIQERLRPYNIINDDSSHFDRKKRFPNN
    

Molecular Weight7642.44 Da

Isoelectric Point (pI)8.39

Net Charge (pH 7.0)0.95

Net Charge (pH 7.4) 0.62

Charge Density (pH 7.0) 0.0141

GRAVY Index-0.89

Hydrophobic Moment 0.54

Boman Index-0.15

Instability Index52.79

Aliphatic Index 64.03

Aromaticity 0.0896

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3312.35

LogP -36.27

H-bond Donors 114.0

H-bond Acceptors 106.0

Rotatable Bonds 252.0

Heavy Atoms 539.0

Ring Count 14.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381461 VERIFIED: YES

Provenance & Taxonomy

OrganismHaplochromis burtoni [Animal]

FamilyProgonadoliberin

Tax ID8153

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour