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MYP_097917
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Basic Information
HYL-17 (Derived from HYL)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C87H166N22O19
Standard
Sequence
KILSSLLKKLKKIIAK
Physicochemical Analysis
1824.38 Da
10.70
5.75
5.54
0.3596
0.34
0.72
-0.02
6.92
176.88
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
696.40
-2.23
25.0
25.0
71.0
128.0
0.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193615 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells
364 μM
LC50
PaperAntimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0200095 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
1.4 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0234379 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-negative bacteria: Escherichia coli
16 μM
MIC
PaperAntimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0241152 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacteria: Staphylococcus aureus 6271
32 μM
MIC
PaperAntimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0304476 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 5482
5 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
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