‹ ›
MYP_097889
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
17 amino acids
C73H122N22O29S
Standard
Sequence
AGDDQGLDKCVPNSKEK
Physicochemical Analysis
1803.94 Da
4.68
-1.21
-1.42
-0.0712
-1.39
0.40
-0.33
11.31
45.88
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
853.80
-11.62
28.0
29.0
63.0
125.0
1.0
18.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0195349 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 22595270 PMID22595270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22595270/
RECORD: Rec_0214023 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Lactoferrin-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Replication inhibition
Influenza A virus (A/Roma-ISS/2/08 H1N1) | MDCK cells
0.0000037±0.00000035 μM
EC50
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperBovine lactoferrin-derived peptides as novel broad-spectrum inhibitors of influenza virus. | Ammendolia MG, Agamennone M, Pietrantoni A, Lannutti F, Siciliano RA, De Giulio B, Amici C, Superti F. | Pathog Glob Health. 2012 Mar;106(1):12-9. | DOI:10.1179/2047773212Y.0000000004 | PMID:22595270 PMID22595270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22595270/
RECORD: Rec_0217302 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0218340 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Viral strain
PMID26492266;22595270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26492266/
RECORD: Rec_0252089 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Influenza A virus (A/Parma/05/06 H3N2):inhibition of viral replication in MDCK cells
0.000007±0.000001 μM
EC50
PaperPubMed PMID: 22595270 PMID22595270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22595270/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records · Page 2 of 3