Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC210H334N58O67S

DescriptionStandard

        MEKLNHNAVTSLNEVSDSELDTILGGSRWQYYRKSKLKISY
    

Molecular Weight4775.31 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)0.59

Net Charge (pH 7.4) 0.31

Charge Density (pH 7.0) 0.0144

GRAVY Index-0.76

Hydrophobic Moment 0.43

Boman Index-0.14

Instability Index34.33

Aliphatic Index 83.17

Aromaticity 0.0976

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2081.06

LogP -21.81

H-bond Donors 74.0

H-bond Acceptors 70.0

Rotatable Bonds 164.0

Heavy Atoms 336.0

Ring Count 6.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112911 VERIFIED: NO

Provenance & Taxonomy

OrganismLactobacillus iners LactinV 03V1-b [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0419785 VERIFIED: NO