Peptide Database

Peptide NameChromogranin-A

Function Ontology

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length445 amino acids

Chemical FormulaC2097H3339N635O759S11

DescriptionStandard

        LPVNSPMTKGDTKVMKCVLEVISDSLSKPSPMPVSPECLETLQGDERILSILRHQNLLKELQDLALQGAKERAQQPLKQQQPPKQQQQQQQQQQQEQQHSSFEDELSEVFENQSPDAKHRDAAAEVPSRDTMEKRKDSDKGQQDGFEATTEGPRPQAFPEPNQESPMMGDSESPGEDTATNTQSPTSLPSQEHVDPQATGDSERGLSAQQQARKAKQEEKEEEEEEEAVAREKAGPEEVPTAASSSHFHAGYKAIQKDDGQSDSQAVDGDGKTEASEALPSEGKGELEHSQQEEDGEEAMVGTPQGLFPQGGKGRELEHKQEEEEEEEERLSREWEDKRWSRMDQLAKELTAEKRLEGEDDPDRSMKLSFRTRAYGFRDPGPQLRRGWRPSSREDSVEARSDFEEKKEEEGSANRRAEDQELESLSAIEAELEKVAHQLQALRRG
    

Molecular Weight49942.46 Da

Isoelectric Point (pI)4.63

Net Charge (pH 7.0)-42.27

Net Charge (pH 7.4) -43.15

Charge Density (pH 7.0) -0.0950

GRAVY Index-1.37

Hydrophobic Moment 0.86

Boman Index-0.31

Instability Index83.90

Aliphatic Index 48.54

Aromaticity 0.0315

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0331020 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyChromogranin/secretogranin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsSer101 Phosphoserine; Ser202 Phosphoserine; Ser290 Phosphoserine; Gly311 Amidation; Ser332 Phosphoserine; Ser392 Phosphoserine; Ser396 Phosphoserine

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor