Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length412 amino acids

Chemical FormulaC2094H3310N540O599S19

DescriptionStandard

        MVKICCSLLLLSLLSVQLKANPGLKVRITQKALEYAKEVGLEILKKNMEKEQFPDLTGYERFGLGNVNYNISRIRVTAVEFPNVSISLMPRSGVKLVIRNASLTIDMNWNIRTWMFKDGGRSTVHISKVFVTAMFSTPLDRMGHTSIPLISCHTTPGDTDIKLNGKSGFLHDFFIKYLKKPIHRRLATNSCPNIKSGIRLIAKDLQSLNVPVRIDDLAEIDYSLNNLEVFRPHIDMDLKGIVYPAGNYTGPPYVAAPFAIPDQNDSMLYLAFSEYFFQTSLFSYYTAGAFNITIEKETCRYLNINTEMFGSIIPEIAKYSVVPYPVMVKLMATEIPLVSLQQDSFTLEILESMEVFAVLPDSNNQSLFTVNVAANTSVALNVFDQKLTGSLCLNRLQFSLIHSNVGSFEVSR
    

Molecular Weight46243.17 Da

Isoelectric Point (pI)8.38

Net Charge (pH 7.0)3.09

Net Charge (pH 7.4) 2.33

Charge Density (pH 7.0) 0.0075

GRAVY Index0.08

Hydrophobic Moment 0.77

Boman Index0.11

Instability Index37.20

Aliphatic Index 101.00

Aromaticity 0.0971

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33725.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310576 VERIFIED: NO

Provenance & Taxonomy

OrganismCoturnix japonica (Japanese quail) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria