Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC724H1149N191O221S10

DescriptionStandard

        MNLLMLTFVICTLLTQVTKGSFAPQKCWKNNIGYCRRRCLDTERYILLCRNKLSCCISIIISHEYTQRPAFPVIHLEDITFDYNYVDSFTGSPVSRLNDLVTFGTTNSAEITALETATFETTMPPPKATTSKTTTPSSPTALTNNQ
    

Molecular Weight16385.67 Da

Isoelectric Point (pI)8.18

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0111

GRAVY Index-0.10

Hydrophobic Moment 0.60

Boman Index0.05

Instability Index55.84

Aliphatic Index 80.82

Aromaticity 0.0890

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6625.72

LogP -72.39

H-bond Donors 238.0

H-bond Acceptors 235.0

Rotatable Bonds 526.0

Heavy Atoms 1146.0

Ring Count 25.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139055 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence