Peptide Database

Peptide Namedichotomin C

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Enzyme modulation ▸ Enzyme inhibition ▸ Cyclooxygenase-inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC33H46N6O9

DescriptionStandard

        GTFLYA
    

Molecular Weight670.75 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0401

GRAVY Index1.00

Hydrophobic Moment 0.15

Boman Index0.59

Instability Index54.22

Aliphatic Index 81.67

Aromaticity 0.3333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 249.28

LogP -0.91

H-bond Donors 9.0

H-bond Acceptors 9.0

Rotatable Bonds 18.0

Heavy Atoms 48.0

Ring Count 2.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0261999 VERIFIED: YES

Provenance & Taxonomy

OrganismStellaria dichotoma [Plant]

FamilyOrbitide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic Cyclooxygenase-inhibitor

TargetP388 cells