Peptide Database

Peptide NameLatarcin 4a

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC136H216N34O34S

DescriptionStandard

        GLKDKFKSMGEKLKQYIQTWKAKF
    

Molecular Weight2903.44 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.1982

GRAVY Index-1.02

Hydrophobic Moment 0.55

Boman Index-0.20

Instability Index-13.53

Aliphatic Index 52.92

Aromaticity 0.1667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1152.02

LogP -6.97

H-bond Donors 40.0

H-bond Acceptors 40.0

Rotatable Bonds 105.0

Heavy Atoms 205.0

Ring Count 5.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424312 VERIFIED: YES

Provenance & Taxonomy

OrganismLachesana tarabaevi [Animal]

FamilyLatarcin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

Targetyeasts P. pastoris, Saccharomyces cerevisiae

Activity18-36 μM

MethodMIC

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