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MYP_097688
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Basic Information
Latarcin 4a
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
24 amino acids
C136H216N34O34S
Standard
Sequence
GLKDKFKSMGEKLKQYIQTWKAKF
Physicochemical Analysis
2903.44 Da
10.00
4.76
4.54
0.1982
-1.02
0.55
-0.20
-13.53
52.92
0.1667
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1152.02
-6.97
40.0
40.0
105.0
205.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0267695 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pichia pastoris GS115
36 μM
MIC
PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0272583 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Latarcin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
P-aeruginosa
>35 μM
MIC
PaperLatarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity. PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0290023 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa PAO1
35 μM
MIC
PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0311800 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Latarcin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S.cerevisiae Y190
18 μM
MIC
PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0313611 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Latarcin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli DH5-alpha
4.5 μM
MIC
PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
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