Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC395H621N109O117S9

DescriptionStandard

        MKTFLFLFAVFFFLTQPRMFFDEKCSRINGRCTESCLKNEELIALCQKNLKCCVTVQPCGRDKGDELDEDSGYNRTRG
    

Molecular Weight9057.40 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.45

Net Charge (pH 7.4) 0.10

Charge Density (pH 7.0) 0.0057

GRAVY Index-0.34

Hydrophobic Moment 0.52

Boman Index-0.10

Instability Index30.95

Aliphatic Index 63.72

Aromaticity 0.1154

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3707.96

LogP -36.63

H-bond Donors 135.0

H-bond Acceptors 127.0

Rotatable Bonds 308.0

Heavy Atoms 630.0

Ring Count 11.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423999 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic