Peptide Database

Peptide NameTrefoil factor 3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC282H427N75O90S8

DescriptionStandard

        QEFVGLSPSQCMVPANVRVDCGYPTVTSEQCNNRGCCFDSSIPNVPWCFKPLQETECTF
    

Molecular Weight6564.38 Da

Isoelectric Point (pI)4.36

Net Charge (pH 7.0)-3.30

Net Charge (pH 7.4) -3.61

Charge Density (pH 7.0) -0.0559

GRAVY Index-0.20

Hydrophobic Moment 0.40

Boman Index0.04

Instability Index71.09

Aliphatic Index 51.02

Aromaticity 0.1017

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2634.81

LogP -31.44

H-bond Donors 93.0

H-bond Acceptors 95.0

Rotatable Bonds 202.0

Heavy Atoms 455.0

Ring Count 13.0

Amide Bonds 66.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0389043 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyTrefoil factor

Tax ID10116

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide11-37; 21-36; 31-48; 57-57

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour