Peptide Database

Peptide NameAlemtuzumab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length451 amino acids

Chemical FormulaC2210H3428N586O674S15

DescriptionStandard

        QVQLQESGPGLVRPSQTLSLTCTVSGFTFTDFYMNWVRQPPGRGLEWIGFIRDKAKGYTTEYNPSVKGRVTMLVDTSKNQFSLRLSSVTAADTAVYYCAREGHTAAPFDYWGQGSLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight49471.36 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)6.55

Net Charge (pH 7.4) 5.56

Charge Density (pH 7.0) 0.0145

GRAVY Index-0.39

Hydrophobic Moment 0.58

Boman Index0.01

Instability Index42.34

Aliphatic Index 70.33

Aromaticity 0.0931

Extinction Coeff. Reduced 70820.00

Extinction Coeff. Oxidized 71445.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174461 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]; Rattus norvegicus [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10090;10116;10029

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory

Half-Life289 hrs

RECORD: Rec_0375855 VERIFIED: NO