Peptide Database

Peptide NameNPLP-1-8

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC109H175N35O37S

DescriptionStandard

        NIQTLVRDWNLPRQQSMAADNE
    

Molecular Weight2599.83 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0559

GRAVY Index-1.03

Hydrophobic Moment 0.53

Boman Index-0.24

Instability Index79.69

Aliphatic Index 75.45

Aromaticity 0.0455

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1216.12

LogP -14.47

H-bond Donors 40.0

H-bond Acceptors 37.0

Rotatable Bonds 86.0

Heavy Atoms 182.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013037 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyNPLP-1

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0213187 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/