Peptide Database

Peptide NameHepcidin antimicrobial peptide 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC428H677N119O127S15

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPLNGVQELEEAGSNDTPVAAHQEMSMESWMMPSRVREKRQSHISMCYWCCNCCRANKGCGYCCKF
    

Molecular Weight10002.65 Da

Isoelectric Point (pI)6.69

Net Charge (pH 7.0)-0.40

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0044

GRAVY Index0.14

Hydrophobic Moment 0.47

Boman Index0.09

Instability Index56.56

Aliphatic Index 71.56

Aromaticity 0.0778

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3930.49

LogP -40.25

H-bond Donors 145.0

H-bond Acceptors 144.0

Rotatable Bonds 329.0

Heavy Atoms 689.0

Ring Count 14.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149741 VERIFIED: NO

Provenance & Taxonomy

OrganismPagrus auriga [Animal]

FamilyHepcidin

Tax ID63415

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0364211 VERIFIED: NO