Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC301H475N81O94S8

DescriptionStandard

        MRYFQMAKQQMNLVEIEAMNSLQELTLEELDNVLGAGGGVIQTISHECRMNSWQFLFTCCS
    

Molecular Weight6989.00 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-4.43

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0726

GRAVY Index-0.02

Hydrophobic Moment 0.53

Boman Index0.10

Instability Index49.25

Aliphatic Index 83.11

Aromaticity 0.0820

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2857.45

LogP -28.05

H-bond Donors 99.0

H-bond Acceptors 99.0

Rotatable Bonds 239.0

Heavy Atoms 484.0

Ring Count 7.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297273 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus salivarius K12 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence