Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length195 amino acids

Chemical FormulaC959H1532N268O264S12

DescriptionStandard

        PKALPMAREPMLLLAVTDFVANSAAFTYFTAGALHKNISSDMVPRQFPLQLRTKNMGVFSPLLQERYQDRPMELHLWARRQPLLSCHADALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITRNRLGGTVRLTGGLSPVCTMDPSACLCQAQGLSVPQVKRLETLLKFGLWLFGVPRANSECCPHSVP
    

Molecular Weight21424.84 Da

Isoelectric Point (pI)9.43

Net Charge (pH 7.0)7.35

Net Charge (pH 7.4) 6.93

Charge Density (pH 7.0) 0.0377

GRAVY Index0.09

Hydrophobic Moment 0.55

Boman Index0.09

Instability Index57.06

Aliphatic Index 93.03

Aromaticity 0.0718

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8393.37

LogP -105.15

H-bond Donors 294.0

H-bond Acceptors 288.0

Rotatable Bonds 684.0

Heavy Atoms 1503.0

Ring Count 38.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244470 VERIFIED: NO

Provenance & Taxonomy

OrganismScytalopus superciliaris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria