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MYP_097549
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Basic Information
moroPC-NH2 (moronecidin-like peptide; fish, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
22 amino acids
C115H175N33O25
Standard
Sequence
FFGHLFRGIINVGKHIHGLLSG
Physicochemical Analysis
2419.83 Da
11.00
2.02
1.66
0.0918
0.60
0.76
0.37
14.98
119.55
0.1364
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
911.70
-5.45
32.0
30.0
79.0
173.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0268812 VERIFIED: YES
Provenance & Taxonomy
Parachaenichthys charcoti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus pyogenes (ATCC 19615)
2.5 μM
MIC
PMID28122029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28122029/
RECORD: Rec_0285403 VERIFIED: YES
Provenance & Taxonomy
Parachaenichthys charcoti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli DH5alpha
5 μM
MIC
PMID28122029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28122029/
RECORD: Rec_0288174 VERIFIED: YES
Provenance & Taxonomy
Parachaenichthys charcoti [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0294641 VERIFIED: YES
Provenance & Taxonomy
Parachaenichthys charcoti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Enterobacter cloacae ATCC 13047
25 μM
MIC
PaperCharacterization of Two Antimicrobial Peptides from Antarctic Fishes (Notothenia coriiceps and Parachaenichthys charcoti). PLoS One. 2017. DOI:10.1371/journal.pone.0170821. PMID28122029
RECORD: Rec_0315587 VERIFIED: YES
Provenance & Taxonomy
Parachaenichthys charcoti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis (ATCC 29212)
25 μM
MIC
PMID28122029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28122029/
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