Peptide Database

Peptide NameHelicostatin-8

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Invertebrate inhibitory neuropeptide

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Invertebrate inhibitory neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC48H66N10O12

DescriptionStandard

        YSKFNFGL
    

Molecular Weight975.10 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0948

GRAVY Index-0.06

Hydrophobic Moment 0.24

Boman Index0.21

Instability Index-10.04

Aliphatic Index 48.75

Aromaticity 0.3750

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 376.59

LogP -2.10

H-bond Donors 13.0

H-bond Acceptors 13.0

Rotatable Bonds 30.0

Heavy Atoms 70.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013291 VERIFIED: YES

Provenance & Taxonomy

OrganismHelicoverpa armigera [Animal]

FamilyHelicostatin

Tax ID29058

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min

RECORD: Rec_0024227 VERIFIED: YES

Provenance & Taxonomy

OrganismHelicoverpa armigera [Animal]

FamilyAllatostatin

Tax ID29058

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate inhibitory neuropeptide

RECORD: Rec_0065981 VERIFIED: NO

Provenance & Taxonomy

OrganismHelicoverpa armigera Noctuidae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0083519 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/