Peptide Database

Peptide NameMu-agatoxin-Hc1a (Mu-AGTX-Hc1a; Curtatoxin-1; CT-I)

Function Ontology

Insecticidal/Pest control ▸ Insecticidal activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC165H242N50O58S8

DescriptionStandard

        SCVGEYGRCRSAYEDCCDGYYCNCSQPPYCLCRNNN
    

Molecular Weight4110.51 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-1.62

Net Charge (pH 7.4) -1.95

Charge Density (pH 7.0) -0.0449

GRAVY Index-0.79

Hydrophobic Moment 0.43

Boman Index-0.20

Instability Index55.78

Aliphatic Index 21.67

Aromaticity 0.1389

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1776.43

LogP -24.61

H-bond Donors 69.0

H-bond Acceptors 65.0

Rotatable Bonds 126.0

Heavy Atoms 281.0

Ring Count 7.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053619 VERIFIED: YES

Provenance & Taxonomy

OrganismHololena curta [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Insecticidal

Targetdomestica

Activity20 μg/g

MethodLD50

RECORD: Rec_0357952 VERIFIED: NO

Provenance & Taxonomy

OrganismHololena curta [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-17; 9-22; 16-32; 24-40

Bio-Activity Profile

Function

Toxin