‹ ›
MYP_097435
← PREVIOUS NEXT → BACK
Basic Information
Ticin A1(Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
42 amino acids
C178H294N50O61S3
Standard
Sequence
SLGVTLGAAGLYTATQTIATQIWKCGAVLTTSAECSRTGNSC
Physicochemical Analysis
4206.73 Da
7.69
0.43
0.18
0.0103
0.37
0.48
0.21
16.85
83.81
0.0476
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1789.69
-25.72
68.0
65.0
135.0
292.0
3.0
44.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0031259 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Gram-positive
PaperPubMed PMID: 26231642 PMID26231642 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26231642/
RECORD: Rec_0120622 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0211787 VERIFIED: NO
Provenance & Taxonomy
Bacillus thuringiensis BMB3201 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID26231642 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26231642/
RECORD: Rec_0254821 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
APD analysis reveals that the sequence of this peptide most resembles (41.7% similarity) Brevinin-2ISc. Activity spectrum is similar to Ticin A4. Chemical modifications such as dehydration are to be determined
Bio-Activity Profile
Antimicrobial
PaperThree novel lantibiotics ticin A1, A3, and A4 have extremely stable properties and are promising food bio-preservatives.
RECORD: Rec_0296625 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]; Bacteria [Bacterium]
1428; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID26196691 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26196691/