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MYP_097433
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Basic Information
M4
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
11 amino acids
C55H104N16O13
Standard
Sequence
KRKILILIGSG
Physicochemical Analysis
1197.51 Da
11.17
2.76
2.55
0.2507
0.65
0.32
0.14
66.03
177.27
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
488.49
-2.75
18.0
16.0
44.0
84.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0083840 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Cytotoxic Anticancer Non-antibacterial Non-cytotoxic
Escherichia coli; Staphylococcus xylosus; U-937 cells
>64 μM
MIC; LD50; MTC
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/ PatentEP2905288A1
RECORD: Rec_0096115 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial Antimicrobial
Staphylococcus xylosus
>64 μM
MIC
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0110010 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxic Anticancer Non-cytotoxic
U-937 cells
>64 μM
LD50
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0183078 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxic Anticancer Non-cytotoxic
U-937 cells
>64 μM
MTC
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0252239 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial Antimicrobial
Escherichia coli DH5alpha
>64 μM
MIC
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
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