Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC728H1161N197O215S11

DescriptionStandard

        METQRASLCLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNELCWAWLVTLECPCYLWACVC
    

Molecular Weight16465.91 Da

Isoelectric Point (pI)5.04

Net Charge (pH 7.0)-3.57

Net Charge (pH 7.4) -3.97

Charge Density (pH 7.0) -0.0244

GRAVY Index-0.13

Hydrophobic Moment 0.77

Boman Index0.00

Instability Index42.02

Aliphatic Index 94.79

Aromaticity 0.0685

Extinction Coeff. Reduced 31970.00

Extinction Coeff. Oxidized 32595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6575.61

LogP -58.72

H-bond Donors 235.0

H-bond Acceptors 223.0

Rotatable Bonds 528.0

Heavy Atoms 1151.0

Ring Count 27.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143420 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal