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MYP_097387
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Basic Information
peptide derived from bovine alphaS1-casein (194-199)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C35H53N7O9S
Standard
Sequence
TTMPLW
Physicochemical Analysis
747.90 Da
5.18
-0.60
-0.79
-0.1003
0.30
0.15
0.42
121.03
65.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
256.28
-0.39
9.0
10.0
19.0
52.0
3.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0231887 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperMcClean S., Beggs L. B., Welch R.. Antimicrobial activity of antihypertensive food-derived peptides and selected alanine analogues. Food Chem., 146, 443-447, 2014.
RECORD: Rec_0232681 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperMcClean S., Beggs L. B., Welch R.. Antimicrobial activity of antihypertensive food-derived peptides and selected alanine analogues. Food Chem., 146, 443-447, 2014.
RECORD: Rec_0243441 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
16 μM
IC50
PaperAngiotensin I-Converting Enzyme Inhibitory Activity of the C-Terminal Hexapeptide of αs1- Casein | Maruyama, S. et al. | DOI: 10.1080/00021369.1987.10868415 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0248953 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
51 μM
IC50
PaperAngiotensin I Converting Enzyme Inhibitory Peptides Derived from Bovine Milk Proteins | Pihlanto-Leppala, A. et al. | DOI: 10.1016/S0958-6946(98)00048-X Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0253199 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 11775
193 μM
MIC
PMID24176365 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24176365/
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