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MYP_097387
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Basic Information
peptide derived from bovine alphaS1-casein (194-199)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C35H53N7O9S
Standard
Sequence
TTMPLW
Physicochemical Analysis
747.90 Da
5.18
-0.60
-0.79
-0.1003
0.30
0.15
0.42
121.03
65.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
256.28
-0.39
9.0
10.0
19.0
52.0
3.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0176901 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
ACE inhibitory peptide
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
16 μM
IC50
RECORD: Rec_0181908 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
22.2 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0199097 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBioactive peptides derived from milk proteins and their health beneficial potentials: an update. PMID21773582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21773582/
RECORD: Rec_0223028 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; synthetic construct [Synthetic]; Homo sapiens [Animal]; Hydrolysis with [Plant]; Poaceae [Plant]
9913; 32630; 9606; 33090; 4479
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAntihypertensive peptides: production, bioavailability and incorporation into foods PMID21185549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185549/
RECORD: Rec_0231833 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
16.0
IC50
PaperMaruyama S., Mitachi H., Awaya J., Kurono M., Tomizuka N., Suzuki H.. Angiotensin I-converting enzyme inhibitory activity of the C-terminal hexapeptide of alphas1-casein. Agric. Biol. Chem., 51, 2557-2561, 1987.
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