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MYP_097387
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Basic Information
peptide derived from bovine alphaS1-casein (194-199)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C35H53N7O9S
Standard
Sequence
TTMPLW
Physicochemical Analysis
747.90 Da
5.18
-0.60
-0.79
-0.1003
0.30
0.15
0.42
121.03
65.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
256.28
-0.39
9.0
10.0
19.0
52.0
3.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003703 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory
PaperMigliore-Samour D., Floc'h F., Jolles P.. Biologically active casein peptides implicated in immunomodulation. J. Dairy Res., 56, 357-362, 1989.
RECORD: Rec_0029423 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
ACE-inhibitory peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
13.6 mmHg
SBP decrease
PaperAntihypertensive Peptides Specific to Lactobacillus helveticus Fermented Milk
RECORD: Rec_0034438 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
51 μM
IC50
PaperAngiotensin I Converting Enzyme Inhibitory Peptides Derived from Bovine Milk Proteins (
RECORD: Rec_0040575 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli; Staphylococcus aureus; Candida albicans
MIC
PaperAntimicrobial activity of antihypertensive food-derived peptides and selected alanine analogues | McClean, S. et al. | DOI: 10.1016/j.foodchem.2013.09.094 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0041716 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperImpact of milk processing on the generation of peptides during digestion
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